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• Deebo Samuel: In line to practice Wednesday
  28 Sep | 19:31 - Samuel (foot) is expected to return to practice Wednesday, David Lombardi of The Athletic reports. Visit RotoWire.com for more analysis on this update.
• Jimmy Garoppolo: May be able to practice Wednesday
  28 Sep | 19:25 - Coach Kyle Shanahan is "still not sure" if Garoppolo (ankle) will be able to practice Wednesday, Matt Barrows of The Athletic reports. Visit RotoWire.com for more analysis on this update.
• Raheem Mostert: Will be under evaluation Wednesday
  28 Sep | 19:19 - Coach Kyle Shanahan said Mostert (knee) will be looked at Wednesday, Cam Inman of The San Jose Mercury News reports. Visit RotoWire.com for more analysis on this update.
• George Kittle: To be evaluated Wednesday
  28 Sep | 19:09 - Coach Kyle Shanahan said the 49ers will assess Kittle (knee) on Wednesday, Cam Inman of The San Jose Mercury News reports. Visit RotoWire.com for more analysis on this update.
• Sammy Watkins: Available Monday
  28 Sep | 19:01 - Watkins (concussion/neck) is listed as active Monday at Baltimore, Matt McMullen of the Chiefs' official site reports. Visit RotoWire.com for more analysis on this update.
• Jordan Reed: Heading to injured reserve
  28 Sep | 18:42 - The 49ers placed Reed (knee) on injured reserve Monday, Nick Wagoner of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Henry Ruggs: Concern for Week 4 status
  28 Sep | 18:29 - Coach Jon Gruden noted Monday that the Raiders are "concerned about both" Ruggs (hamstring) and Bryan Edwards (ankle)," Vic Tafur of The Athletic reports. Visit RotoWire.com for more analysis on this update.
• Bryan Edwards: Spotted with walking boot
  28 Sep | 18:22 - Edwards (ankle) was sporting a walking boot on his right foot Monday, Tashan Reed of The Athletic reports. Visit RotoWire.com for more analysis on this update.
• Chris Godwin: Likely to miss time
  28 Sep | 18:12 - The Buccaneers expect Godwin (hamstring) to miss some time, Rick Stroud of the Tampa Bay Times reports. Visit RotoWire.com for more analysis on this update.
• Jamison Crowder: Could return to action Thursday night
  28 Sep | 17:57 - Crowder (hamstring) "sounds like a game-time decision" for Thursday night's game against the Broncos, Rich Cimini of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Michael Pittman: Slated to miss time
  28 Sep | 17:18 - Coach Frank Reich confirmed Monday that Pittman underwent surgery to address a lower leg injury that the wideout suffered Sunday against the Jets, Andrew Walker of the Colts' official site reports. Visit RotoWire.com for more analysis on this update.
• Breshad Perriman: Won't play Thursday
  28 Sep | 17:04 - Coach Adam Gase said Monday that Perriman (ankle) won't suit up against the Broncos on Thursday, Rich Cimini of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Tyrod Taylor: Not ruled out for Week 4
  28 Sep | 16:52 - Coach Anthony Lynn said Monday that he's "not in a position" to rule Taylor (chest) out for Sunday's game against the Buccaneers, Gilbert Manzano of The Orange County Register reports. Visit RotoWire.com for more analysis on this update.
• Michael Pittman: Likely to miss multiple weeks
  28 Sep | 16:21 - Pittman underwent surgery to address a calf injury sustained during Monday's loss to the Jets and could be out until Week 8, Ian Rapoport of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• Travis Homer: Could handle more reps
  28 Sep | 15:54 - Homer could be in line for more volume following news that Carson suffered a first-degree knee sprain in Sunday's 38-31 win over the Cowboys, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Carlos Hyde: Increased duties on tap?
  28 Sep | 15:41 - Hyde could log more touches moving forward following news that Carson suffered a first-degree knee sprain during Sunday's 38-31 win over the Cowboys, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Phillip Lindsay: Looks on track for Thursday
  28 Sep | 14:30 - Coach Vic Fangio said Monday that Lindsay (toe) is "trending in the right direction" to suit up Thursday in New York, Kyle Newman of The Denver Post reports. Visit RotoWire.com for more analysis on this update.
• Dallas Goedert: Without timetable for return
  28 Sep | 13:38 - Coach Doug Pederson said Monday that Goedert (ankle) will miss "some time," Vaughn Johnson of the Eagles' official site reports. Visit RotoWire.com for more analysis on this update.
• Tarik Cohen: ACL tear confirmed
  28 Sep | 13:30 - Coach Matt Nagy confirmed Monday that Cohen suffered a torn ACL during Sunday's win over the Falcons, Adam Hoge of NBC Sports Chicago reports. Visit RotoWire.com for more analysis on this update.
• Mitchell Trubisky: Officially relegated to backup role
  28 Sep | 13:24 - Trubisky will transition to a backup role Week 4 while Nick Foles handles the starting gig, Brad Biggs of the Chicago Tribune reports. Visit RotoWire.com for more analysis on this update.
• Nick Foles: Confirmed as Week 4 starter
  28 Sep | 13:15 - Coach Matt Nagy said Monday that Foles will start against the Colts on Sunday, Brad Biggs of the Chicago Tribune reports. Visit RotoWire.com for more analysis on this update.
• Chris Carson: Nursing first-degree sprain
  28 Sep | 13:09 - Carson's knee injury has been diagnosed as a first-degree sprain, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Chris Godwin: MRI on tap
  28 Sep | 12:29 - Godwin (hamstring) is scheduled to receive an MRI on Monday, Scott Smith of the Buccaneers' official site reports. Visit RotoWire.com for more analysis on this update.
• Chris Carson: Could play Week 4
  28 Sep | 12:00 - Carson (knee) had an MRI reveal a minor sprain Monday, Tom Pelissero of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• DeSean Jackson: Believed to be nursing minor strain
  28 Sep | 10:37 - Jackson (hamstring) is set to undergo medical evaluation Monday for what the Eagles believe is a minor strain, Mike Garafolo of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• DJ Chark: Getting more tests
  28 Sep | 09:49 - Chark (chest/back) is still undergoing testing Monday morning, John Reid of The Florida Times-Union reports. Visit RotoWire.com for more analysis on this update.
• Carson Wentz: Won't be benched
  28 Sep | 09:21 - Coach Doug Pederson said it would be a "knee jerk-reaction" to bench Wentz in favor of Jalen Hurts, Jeff McLane of The Philadelphia Inquirer reports. Visit RotoWire.com for more analysis on this update.
• Aaron Rodgers: Remains flawless on SNF
  28 Sep | 04:04 - Rodgers completed 21 of 32 pass attempts for 283 yards and three touchdowns in Sunday's 37-30 win over the Saints. Visit RotoWire.com for more analysis on this update.
• Allen Lazard: Breaks out on SNF
  28 Sep | 03:00 - Lazard had six receptions (eight targets) for 146 yards and a touchdown in Sunday's 37-30 win over New Orleans. Visit RotoWire.com for more analysis on this update.
• Aaron Jones: Finds end zone in victory
  28 Sep | 02:38 - Jones rushed 16 times for 69 yards and a touchdown, adding two receptions for 17 yards in Sunday's 37-30 win over the Saints. Visit RotoWire.com for more analysis on this update.
• Alvin Kamara: Monster receiving performance
  28 Sep | 02:04 - Kamara rushed just six times for 58 yards, but corralled 13 receptions (14 targets) for 139 yards and two touchdowns in Sunday's 37-30 loss to the Packers. Visit RotoWire.com for more analysis on this update.
• Jared Cook: Heads to locker room with limp
  27 Sep | 22:52 - Cook came up noticeably limping after a catch in the second half of Sunday's game against the Packers and was taken to the locker room, Amie Just of NOLA.com reports. Visit RotoWire.com for more analysis on this update.
• Tyler Lockett: Hauls in three TDs in win
  27 Sep | 22:40 - Lockett caught nine of 13 targets for 100 yards and three touchdowns in Sunday's 38-31 win over the Cowboys. Visit RotoWire.com for more analysis on this update.
• Russell Wilson: Makes history in shootout win
  27 Sep | 22:32 - Wilson completed 27 of 40 passes for 315 yards and five touchdowns during Sunday's 38-31 win over the Cowboys. He added 22 rushing yards on six carries. Visit RotoWire.com for more analysis on this update.
• Michael Gallup: Breaks out in Week 3 loss
  27 Sep | 22:12 - Gallup caught six of nine targets for 138 yards and a touchdown in Sunday's 38-31 loss to the Seahawks. Visit RotoWire.com for more analysis on this update.
• Dak Prescott: Huge numbers in loss
  27 Sep | 21:59 - Prescott completed 37 of 57 passes for 472 yards and three touchdowns with two interceptions in Sunday's 38-31 loss to the Seahawks. Visit RotoWire.com for more analysis on this update.
• Kyler Murray: Commits three turnovers in loss
  27 Sep | 21:13 - Murray completed 23 of 35 pass attempts for 270 yards, two touchdowns and three interceptions Sunday against the Lions. He also carried five times for 29 yards and a touchdown in the 26-23 loss. Visit RotoWire.com for more analysis on this update.
• D.J. Moore: Makes two catches
  27 Sep | 21:04 - Moore caught two of four targets for 65 yards during Sunday's 21-16 win over the Chargers. Visit RotoWire.com for more analysis on this update.
• Kenny Golladay: Finds end zone in debut
  27 Sep | 20:56 - Golladay caught six of seven targets for 57 yards and a touchdown during Sunday's 26-23 win over the Cardinals. Visit RotoWire.com for more analysis on this update.
• Kenyan Drake: Accounts for 78 scrimmage yards
  27 Sep | 20:53 - Drake carried 18 times for 73 yards and caught his only target for an additional six yards during Sunday's 26-23 loss to the Lions. Visit RotoWire.com for more analysis on this update.
• Chris Carson: Dealing with knee sprain
  27 Sep | 20:51 - Coach Pete Carroll clarified Carson's injury as a knee sprain in the post-game press conference after Sunday's win over Dallas, Curtis Crabtree of Sports Radio KJR reports. Visit RotoWire.com for more analysis on this update.
• Melvin Gordon: Shut down by stout Bucs front
  27 Sep | 20:33 - Gordon collected 26 rushing yards on eight carries, also catching four of six targets for 12 receiving yards during Sunday's 28-10 loss to the Buccaneers. Visit RotoWire.com for more analysis on this update.
• Rob Gronkowski: Emerges in offense during win
  27 Sep | 20:18 - Gronkowski secured six of seven targets for 48 yards in the Buccaneers' 28-10 win over the Broncos on Sunday. Visit RotoWire.com for more analysis on this update.
• Mike Evans: Maximizes catches in Week 3 win
  27 Sep | 20:10 - Evans secured both of his targets for a pair of one-yard touchdowns in the Buccaneers' 28-10 win over the Broncos on Sunday. Visit RotoWire.com for more analysis on this update.
• Tom Brady: Best game yet as Buc
  27 Sep | 19:55 - Brady completed 25 of 38 passes for 297 yards with three touchdowns and no interceptions in the Buccaneers' 28-10 win over the Broncos on Sunday. He also netted zero yards on five rushes and had one fumble, but it was recovered by the offense. Visit RotoW
• Chris Carson: Hurts leg late against Dallas
  27 Sep | 19:53 - Carson went to the medical tent after having his leg twisted awkwardly in the fourth quarter of Sunday's game against the Cowboys, and Bob Condotta of The Seattle Times reports that Carson's unlikely to return to the game. Visit RotoWire.com for more anal
• Keenan Allen: Impressive day despite loss
  27 Sep | 19:32 - Allen caught 13 of his 19 targets for 136 yards and a touchdown in the 21-16 loss Sunday to the Panthers. Visit RotoWire.com for more analysis on this update.
• Matt Ryan: Inefficient Week 3 outing
  27 Sep | 19:24 - Ryan was 19-for-38 passing with 238 yards, one touchdown, and one interception during Sunday's 30-26 loss to Chicago. Visit RotoWire.com for more analysis on this update.
• Zach Ertz: Double-digit targets in tie
  27 Sep | 19:13 - Ertz corralled seven of 10 targets for 70 receiving yards during Sunday's 23-23 tie against the Bengals. Visit RotoWire.com for more analysis on this update.
• Chris Godwin: Won't return Sunday
  27 Sep | 18:59 - Godwin is ruled out to return to Sunday's game against the Broncos due to a hamstring injury, Scott Smith of the Buccaneers' official site reports. Visit RotoWire.com for more analysis on this update.
• A.J. Green: Slow start continues
  27 Sep | 18:55 - Green hauled in five of six targets for 36 receiving yards during Sunday's 23-23 tie against the Eagles. Visit RotoWire.com for more analysis on this update.
• Tyler Boyd: Double-digit catches against Eagles
  27 Sep | 18:40 - Boyd pulled down 10 of 13 targets for 125 receiving yards during Sunday's 23-23 tie against the Eagles. Visit RotoWire.com for more analysis on this update.
• Dallas Goedert: Likely to miss time
  27 Sep | 18:39 - Goedert is "expected to miss some time" after injuring his left ankle during Sunday's 23-23 tie with the Bengals, Ian Rapoport of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• Calvin Ridley: Hits century mark again
  27 Sep | 18:23 - Ridley caught five of his 13 targets for a total of 110 receiving yards during Sunday's 30-26 loss to Chicago. Visit RotoWire.com for more analysis on this update.
• Derrick Henry: Finds end zone twice
  27 Sep | 18:08 - Henry carried the ball 26 times for 119 yards and two touchdowns in the team's Week 3 win over the Vikings. He also added two receptions for 11 yards. Visit RotoWire.com for more analysis on this update.
• Miles Sanders: Produces against Bengals
  27 Sep | 18:03 - Sanders registered 95 rushing yards on 18 carries while catching four of his eight targets for 12 receiving yards during Sunday's 23-23 tie against Cincinnati. Visit RotoWire.com for more analysis on this update.
• Nick Chubb: Another two scores
  27 Sep | 17:37 - Chubb carried the ball 19 times for 108 yards and two touchdowns in the team's Week 3 win over Washington. He also added one reception for two yards. Visit RotoWire.com for more analysis on this update.
• Bryan Edwards: Misses most of second half
  27 Sep | 17:34 - Edwards (ankle) missed the majority of the second half of Sunday's 36-20 loss to the Patriots, Levi Edwards of the Raiders' official site reports. Visit RotoWire.com for more analysis on this update.
• Dalvin Cook: Totals 199 yards
  27 Sep | 17:24 - Cook rushed the ball 22 times for 181 yards and a touchdown in Week 3 against the Titans. He also added two receptions for 18 yards. Visit RotoWire.com for more analysis on this update.
• Jared Goff: Second half comeback not enough
  27 Sep | 17:22 - Goff completed 23 of 32 passes for 321 yards, two touchdowns, a two-point conversion and an interception in Sunday's 35-32 loss to Buffalo. He also rushed twice for four yards and a touchdown. Visit RotoWire.com for more analysis on this update.
• Michael Pittman: Exits game with ankle injury
  27 Sep | 17:22 - Pittman was forced out of Sunday's game against the Jets with an ankle injury, Andrew Walker of the Colts' official site reports. Visit RotoWire.com for more analysis on this update.
• Sony Michel: Breaks off a couple long runs
  27 Sep | 16:39 - Michel rushed nine times for 117 yards and caught both of his targets for another 23 yards in Sunday's 36-20 win over the Raiders. Visit RotoWire.com for more analysis on this update.
• David Johnson: Finds end zone in loss
  27 Sep | 16:34 - Johnson rushed 13 times for 23 yards and a touchdown and caught two of three targets for 23 yards in Sunday's 28-21 loss to the Steelers. Visit RotoWire.com for more analysis on this update.
• Jerick McKinnon: Hurts ribs Sunday
  27 Sep | 16:32 - McKinnon emerged from Sunday's 36-9 win against the Giants with a rib injury, Nick Wagoner of ESPN.com reports. Overall, McKinnon had 14 carries for 38 yards and one touchdown while reeling in three of four targets for 39 yards. Visit RotoWire.com for mor
• Darren Waller: Non-factor in Week 3 loss
  27 Sep | 16:29 - Waller (knee) caught two of four targets for nine yards in Sunday's 36-20 loss to the Patriots. Visit RotoWire.com for more analysis on this update.
• JuJu Smith-Schuster: Scores third touchdown
  27 Sep | 16:24 - Smith-Schuster caught four of five targets for 43 yards and a touchdown during Sunday's 28-21 win over the Texans. Visit RotoWire.com for more analysis on this update.
• Jordan Reed: Won't return Sunday
  27 Sep | 15:18 - The 49ers ruled Reed (knee/ankle) out of Sunday's contest versus the Giants, David Lombardi of The Athletic reports. Visit RotoWire.com for more analysis on this update.
• Bryan Edwards: Suffers ankle injury
  27 Sep | 15:18 - Edwards was forced out of Sunday's game against the Patriots with an ankle injury. Visit RotoWire.com for more analysis on this update.
• Nick Foles: Enters game following halftime
  27 Sep | 15:15 - Foles replaced Mitchell Trubisky after halftime of Sunday's game versus the Falcons, Field Yates of ESPN reports. Visit RotoWire.com for more analysis on this update.
• DeSean Jackson: Suffers hamstring injury
  27 Sep | 15:13 - Jackson left Sunday's contest against the Bengals due to a hamstring injury. Visit RotoWire.com for more analysis on this update.
• Mitchell Trubisky: Benched after halftime
  27 Sep | 15:11 - Trubisky was replaced by Nick Foles after halftime of Sunday's game versus the Falcons, Field Yates of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Braxton Berrios: In uniform Sunday
  27 Sep | 14:41 - Berrios (hamstring) is listed as active for Sunday's game against the Colts. Visit RotoWire.com for more analysis on this update.
• Jordan Reed: Getting looked at by training staff
  27 Sep | 14:38 - Reed had his left knee examined on the sideline during the second quarter of Sunday's game versus the Giants, Nick Wagoner of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Diontae Johnson: Possible concussion
  27 Sep | 14:13 - Johnson is being evaluated for a concussion during Sunday's game against the Texans, Dale Lolley of DKPittsburghSports.com reports. Visit RotoWire.com for more analysis on this update.
• Russell Gage: Exits Sunday's game
  27 Sep | 14:08 - Gage is being evaluated for a possible head injury and is questionable to return to Sunday's game against the Bears, Jason Butt of The Atlanta Journal-Constitution reports. Visit RotoWire.com for more analysis on this update.
• Jordan Reed: Returns to game
  27 Sep | 13:56 - Reed (ankle) returned to Sunday's game against the Giants, Nick Wagoner of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Dallas Goedert: Goes to locker room Sunday
  27 Sep | 13:33 - Goedert (ankle) went to the locker room during the first quarter of Sunday's game against the Bengals, Mike Garafolo of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• Wayne Gallman: May get first post-Barkley start
  27 Sep | 12:45 - Gallman lined up with the Giants' first-team offense during warmups, indicating he may be the team's starting running back Sunday versus the 49ers, Jordan Raanan of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Devonta Freeman: Suiting up for debut in New York
  27 Sep | 12:23 - Freeman is listed as active Sunday against the 49ers, Dan Graziano of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Tyrod Taylor: Unlikely for Week 4
  27 Sep | 12:23 - Taylor (chest), who has been ruled out for Sunday's game against the Panthers, is unlikely to gain clearance to play Week 4 at Tampa Bay, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• N'Keal Harry: In uniform Sunday
  27 Sep | 11:45 - Harry (ankle) is listed as active for Sunday's game against the Raiders. Visit RotoWire.com for more analysis on this update.
• Julian Edelman: Listed as active Sunday
  27 Sep | 11:43 - Edelman (knee) is listed as active for Sunday's game against the Raiders. Visit RotoWire.com for more analysis on this update.
• Darren Waller: Listed as active Sunday
  27 Sep | 11:38 - Waller (knee) is listed as active for Sunday's game against the Patriots. Visit RotoWire.com for more analysis on this update.
• Josh Jacobs: Suits up Sunday
  27 Sep | 11:36 - Jacobs (hip) is listed as active for Sunday's game against the Patriots. Visit RotoWire.com for more analysis on this update.
• Julio Jones: Sidelined Week 3
  27 Sep | 11:32 - Jones (hamstring) is inactive for Sunday's game against the Bears. Visit RotoWire.com for more analysis on this update.
• Deebo Samuel: Likely eyeing Week 5 return
  27 Sep | 10:01 - Samuel (foot) should resume practicing during the upcoming week, but the 49ers aren't expecting to bring him back from injured reserve until their Week 5 game against the Dolphins on Oct. 11, Ian Rapoport of NFL Network reports. Visit RotoWire.com for mor
• A.J. Brown: Could be out beyond Week 3
  27 Sep | 09:45 - Brown, who is listed as out for Sunday's game against the Vikings, continues to nurse a "pretty significant" bone bruise in his knee and hasn't responded as well or as quickly to treatment as the Titans had hoped, Adam Schefter of ESPN reports. Visit Roto
• Duke Johnson: Not likely to play Sunday
  27 Sep | 07:51 - Johnson (ankle) looks like a long-shot to play Sunday against the Steelers, according to Ian Rapoport of NFL Network. Visit RotoWire.com for more analysis on this update.
• Michael Thomas: Targets Week 4 return
  27 Sep | 07:41 - Thomas (ankle) was "moving really well" during his Friday workout and hopes to play next weekend against the Lions, ESPN's Adam Schefter reports. Visit RotoWire.com for more analysis on this update.
• Jerry Jeudy: Expected to play in Week 3
  27 Sep | 07:27 - Jeudy (ribs) is expected to suit up for Sunday's game against the Buccaneers, Ian Rapoport of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• Kenny Golladay: Expected to play Sunday
  27 Sep | 07:14 - Golladay (hamstring) is expected to make his season debut Sunday against the Cardinals, Ian Rapoport of NFL Network reports. Visit RotoWire.com for more analysis on this update.
• Josh Jacobs: Likely to play Sunday
  27 Sep | 00:24 - Jacobs (hip) is expected to play Sunday against the Patriots, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Darren Waller: On track to play Week 3
  27 Sep | 00:13 - Waller (knee) is expected to play Sunday at New England, Jeremy Fowler of ESPN.com reports. Visit RotoWire.com for more analysis on this update.
• Julio Jones: Remains game-time decision
  27 Sep | 00:05 - Jones (hamstring) is expected to be a game-time decision for Sunday's game against the Bears, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Davante Adams: Not yet ruled out
  26 Sep | 23:55 - Adams (hamstring) will have until game time Sunday night to illustrate he's healthy enough to play against the Saints, Adam Schefter of ESPN reports. Visit RotoWire.com for more analysis on this update.
• Sammy Watkins: Listed as questionable, practices fully
  26 Sep | 15:29 - Watkins (concussion/neck) is listed as questionable for Monday's contest against the Ravens, Adam Teicher of ESPN.com reports. Visit RotoWire.com for more analysis on this update.